The Facts About 4-Androstenediol

4-Andro may not have been the very first prohormone, but like other prohormones it has been a staple in the supplement industry since the mid 1990’s. They have enjoyed a lot of use by bodybuilders as well as other lifters and athletes. Since then, these compounds have gone through significant transformations, especially since the regulatory changes that were introduced way back in 2004. Of course, there have been several additional regulatory changes. One of the most popular prohormones, 4-Androstenediol has survived and is still going strong in 2025. 

What Is 4-Andro?

4-Andro, also known as 4-DHEA, follows a two-step conversion to become testosterone. Here’s how it works: 4-DHEA converts to 4-androstenediol and is then metabolized into testosterone.

4-Andro And Testosterone

No matter what your experience level is, the natural hormone testosterone plays a major role in muscle growth. It is, in fact, one of the most powerful natural anabolic hormones in the body. Some would say it is the most powerful. Of course, it is true that there are other quite a few effective supplements on the market. Yet prohormones in general and 4-Andro in particular are  cut above and go a long way towards helping you achieve your size and strength goals.

4-Andro Facts

  • It Is A Bulking Prohormone
  • It’s A “Wet” Gainer – It May Cause Water Retention
  • Converts To Testosterone
  • Expect Solid Mass & Strength Gains
  • Increases protein Synthesis – A Key Muscle Growth Trigger
  • Enhances Energy
  • Speeds Recovery
  • Reduces Fatigue 
  • Elevates Mood
  • Increases Sex Drive & Libido

Side Effects

No discussion of prohormones would be complete without mentioning possible sides. Let’s face it, they are close enough to steroids to have side effects. So what are they?

 

They include:

  • Possible Estrogen Conversion – Water Retention, Bloating, and Fat Gain.
  • Possible Hair Loss And Acne.
  • The Potential for Gyno. 

 

The best way to treat these problems is by using an estrogen blocker with your PCT. As far as I’m concerned, you can use one during your cycle if desired.

When’s The Best Time To Take 4-Andro?

You can honestly pick anytime of the day to take it. However, I suggest taking 4-Andro 30-60 minutes before your workout. On off-days, take it at the same time of day. Use on a 8 weeks on / 8 weeks off cycle. I suggest 50-100 mg per day. Make sure you follow a good Post Cycle Therapy program during your off-cycle to maximize your gains.

4-Andro & 19-NOR – A Popular Stack

Some advanced lifters have combined 4-Andro with 19-Norandrostenediol (19-NOR). Specifically, they have used a rotating schedule of both 4-Andro and 1-Androstenediol for an amplified effect. During this rotation, they have been taking 19-NOR every day. 

Is 4-Andro A Steroid?

4-Andro is an enhanced variation of testosterone, and yes it is considered to be close to steroids, like all prohormones. It’s suggested for use by men only, but I’m sure some dedicated female lifters will want to try it. 

One of the questions that invariably comes up when talking about prohormones is this: Is it ethical? Or will the user, who may wish to use only natural supplements, cross over into “drug” territory? 

Most lifters will agree, taking prohormones is certainly borderline. They are that close to steroids. Ultimately, it comes down to you and your personal preference. I suggest doing comprehensive research about prohormones and about PCT before using. 

Do Your Research

I strongly advise anyone interested to NOT just rush in and buy a few bottles. You need to know what you are doing. Otherwise, you will quickly lose all your gains. Why? Because 4-Andro and the other prohormones suppress the body’s natural production of testosterone (yes, like steroids). That means that when you stop, your natural hormonal production is really out of whack.

Total Preparation

The only way to maximize your gains will be to follow a well-planned PCT program. Once you have done your research and are properly prepared (meaning you have your total approach planned), the choice to use 4-Andro is yours and yours alone.

What do I mean by total approach? Have your eating plan in place. What supplements are you taking? Have everything you need. That also includes your PCT. One suggestion I will make is to use creatine during your PCT to help you hang on to your mass. What about training? If you’re making any changes to your routine, have them in place and set to go. 

Summary

While it is true that 4-Andro and all prohormones might be on shaky ethical ground, you can see the impressive benefits. Therefore, do your research, including checking into Federations that have banned prohormones (if you do or ever plan to compete). Once you’ve done that, and make your choice, stop by illpumpyouup.com for all your supplement needs!

 

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